Kombinasi Salam, Pegagan, Alang-Alang, dan Pala Terhadap Fungsi Kardiovaskuler Pasien Hipertensi Esensial
Abstract
Abstract
Hypertension is one of cardiovascular risk factors. This study aims to determine the effect of combinations of bay leaf (Syzygium polyanthum), gotu kola (Centella asiatica), cogon grass (Imperata cylindrica), and nutmeg (Myristica fragrans) to the cardiovascular function of essential hypertensive patient as alternative therapy. The study used a pre experimental quasi and post test design. Sixty new patients which came between Juni-October 2016 that fulfilled inclusion criteria, 18-60 years old with mild hypertension and stable health conditions, and exclusion criteria, doesn’t have severe comorbid disease, pregnant, or have allergic reaction toward given combination of bay, gotu kola, cogon grass, and nutmeg (jamu). The subjects drank given jamu formula twice a day for 56 days. Measurement of blood pressure, heart rate, RPP, PP, and MAP done once a week in Rumah Riset Jamu Tawangmangu. The results showed a decrease in systolic pressure from 147.16 ± 6.46 mmHg to 132.25 ± 11, 21 mmHg with p value = 0.001%, diastolic pressure decreased from 92.16 ± 2.49 mmHg to 77.83 ± 8 , 98 mmHg with p value = 0.001%, mean arterial pressure, heart rate, RPP, and PP also decreased. The results showed that combination of bay leaf, gotu kola, cogon grass, nutmeg can increase cardiovascular function by decreasing in blood pressure, heart rate, RPP, PP, and MAP.
Keywords : hypertension, bay leaf, gotu kola, cogon grass, nutmeg
Abstrak
Hipertensi merupakan faktor resiko terjadinya penyakit kardiovaskular. Penelitian ini bertujuan untuk mengetahui efek ramuan kombinasi daun salam (Syzygium polyanthum), pegagan (Centella asiatica), akar alang-alang (Imperata cylindrica), dan biji pala (Myristica fragrans) terhadap fungsi kardiovaskuler pasien hipertensi esensial sebagai terapi alternatif. Desain penelitian yang digunakan pada penelitian ini adalah quasi eksperimental pre dan post test design. Pasien baru berjumlah 60 orang yang datang pada bulan Juni-Oktober 2016, yang memenuhi kriteria inklusi usia 18-60 tahun dengan hipertensi ringan serta kondisi pasien stabil dan kriteria eksklusi tidak mempunyai penyakit komorbid yang berat, hamil atau adanya alergi terhadap salah satu tanaman dalam kombinasi tersebut Subyek diberi ramuan jamu yang diminum 2 kali setiap hari selama 56 hari. Pengukuran terhadap tekanan darah, heart rate, RPP, PP, dan MAP dilakukan setiap minggu di Rumah Riset Jamu Tawangmangu. Hasil yang didapat menunjukkan penurunan tekanan sistolik dari 147,16 ± 6,46 mmHg menjadi 132,25 ± 11, 21 mmHg dengan nilai p = 0,001%, tekanan diastolik menurun dari 92,16 ± 2,49 mmHg menjadi 77,83 ± 8,98 mmHg dengan nilai p = 0,001%, tekanan arteri rata-rata, heart rate, RPP, dan PP juga mengalami penurunan. Hal ini menunjukkan kombinasi daun salam, pegagan, akar alang-alang, dan biji pala dapat meningkatkan fungsi kardiovaskular dengan menurunkan tekanan sistolik, diastolik, tekanan arteri rata-rata, nilai PP dan RPP.
Kata kunci:hipertensi, salam, pegagan, alang-alang, pala
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