http://ejournal2.litbang.kemkes.go.id/index.php/hsji/issue/feed Health Science Journal of Indonesia 2023-05-11T06:17:46SE Asia Daylight Time Vivi Setiawaty hsji.indonesia@gmail.com Open Journal Systems <p>p-ISSN: <a href="http://issn.pdii.lipi.go.id/issn.cgi?daftar&amp;1291340688&amp;1&amp;&amp;" target="_blank" rel="noopener">2087-7021</a><br> e-ISSN: <a href="http://issn.pdii.lipi.go.id/issn.cgi?daftar&amp;1368762775&amp;1&amp;&amp;" target="_blank" rel="noopener">2338-3437</a><br>Health Science Journal of Indonesia in <a href="https://academic.microsoft.com/journal/2764440062/publication/search?q=Health%20Science%20Journal%20of%20Indonesia&amp;qe=And(Composite(J.JId%253D2764440062)%252CTy%253D%270%27)&amp;f=&amp;orderBy=0">Microsoft Academic</a><br>Health Science Journal of Indonesia in <a href="https://drive.google.com/file/d/1JDI2tMHCF1X3xhuMS4BTMl_tGADZoMHM/view?usp=sharing">Scopus Citation</a><br>Health Science Journal of Indonesia in <a href="https://publons.com/journal/53846/health-science-journal-of-indonesia/" target="_blank" rel="noopener">Publons</a><br>Health Science Journal of Indonesia in <a href="https://app.dimensions.ai/discover/publication?or_facet_source_title=jour.1047699&amp;search_mode=content&amp;search_text=health%20science%20journal%20of%20indonesia&amp;search_type=kws&amp;search_field=full_search" target="_blank" rel="noopener">Dimensions</a><br>Health Science Journal of Indonesia in <a href="https://doaj.org/toc/2338-3437?source=%7B%22query%22%3A%7B%22filtered%22%3A%7B%22filter%22%3A%7B%22bool%22%3A%7B%22must%22%3A%5B%7B%22terms%22%3A%7B%22index.issn.exact%22%3A%5B%222087-7021%22%2C%222338-3437%22%5D%7D%7D%5D%7D%7D%2C%22query%22%3A%7B%22match_all%22%3A%7B%7D%7D%7D%7D%2C%22size%22%3A100%2C%22sort%22%3A%5B%7B%22created_date%22%3A%7B%22order%22%3A%22desc%22%7D%7D%5D%2C%22_source%22%3A%7B%7D%7D" target="_blank" rel="noopener">DOAJ</a><br>Health Science Journal of Indonesia in <a href="https://scholar.google.com/citations?user=kBGNZQcAAAAJ&amp;hl=en" target="_blank" rel="noopener">Google Scholar</a><br>Health Science Journal of Indonesia in <a href="https://scholar.google.com/citations?hl=en&amp;view_op=list_hcore&amp;venue=1Vfarb6oQD4J.2016" target="_blank" rel="noopener">Google Scholar Metrics<br></a>Ristekdikti Accreditation: 30/E/KPT/2018, October 24th, 2017. Available in&nbsp; <a href="https://sinta.ristekbrin.go.id/journals/detail?id=2783" target="_blank" rel="noopener">Sinta<br></a>Accreditation Sertificate <a href="https://ejournal2.litbang.kemkes.go.id/index.php/bpk/accreditation" target="_blank" rel="noopener">here</a>. Status : <strong>Terakreditasi Peringkat 2</strong>. Valid until Vol 12 No 1 Tahun 2021.</p> <p><img src="/public/site/images/isaabdullah/sertifikat_small.jpg"></p> <p>Health Science journal of Indonesia is a journal published by National Institute of Research and Development, Ministry of Health of Republic of Indonesia. The journal began publication in 2010, containing scientific manuscripts related to the health field. Health Science Journal of Indonesia is published two times a year.</p> <p><strong>19</strong> articles of Health Science Journal of Indonesia (HSJI) has been cited by <strong>Scopus</strong>. Click <a href="https://drive.google.com/file/d/1jJ75nwzO0JEGbZmmaqVRrFtFEH9UmNEa/view?usp=sharing" target="_blank" rel="noopener">here</a> for detail (update January 2, 2021).&nbsp;<br>See Google Scholar Profile for Health Science Journal of Indonesia by clicking&nbsp;<a href="https://scholar.google.com/citations?hl=id&amp;user=kBGNZQcAAAAJ" target="_blank" rel="noopener">here</a>.</p> <ul> <li class="show">Total Citations : 409</li> <li class="show">Total Articles : 145</li> <li class="show">h-index : 10</li> <li class="show">i10-index : 10</li> </ul> <p>Google Scholar Metrics click&nbsp;<a title="Google Scholar Metrics" href="https://scholar.google.com/citations?hl=en&amp;view_op=list_hcore&amp;venue=1Vfarb6oQD4J.2016" target="_blank" rel="noopener">here</a>.</p> <ul> <li class="show">h5-index : 3</li> <li class="show">h5-median : 3</li> </ul> http://ejournal2.litbang.kemkes.go.id/index.php/hsji/article/view/6452 The Health Promotion Effectiveness On Mother Knowledge Of Stunting Prevention In Toddlers: Literature Review 2022-12-31T16:04:57SE Asia Standard Time Ghodiq Ufthoni thoni.ghodiqufthoni@gmail.com Bagoes Widjanark thoni.ghodiqufthoni@gmail.com Apoina Kartini thoni.ghodiqufthoni@gmail.com Tri Joko thoni.ghodiqufthoni@gmail.com <p><strong>Background:</strong> The goal of public health promotion is to increase people's capacity for action through direct instruction from and for the general public, in order to enable them to take responsibility for their own well-being. It also aims to develop programs based on getting people involved in social activities that support healthy living. Stunting begins to occur when a child is two years old and occurs when the embryo is still inside the womb. Stunting is a condition when someone's normal level of badness is higher than the normal level of badness for someone else. Aim examine the effect of health promotion on mothers' knowledge about stunting prevention in toddlers.</p> <p><strong>Method:</strong> Literature review is done by searching on direct science sites, Pubmed, and google scholar. They used the critical word The effect of health promotion on mothers' knowledge of stunting prevention in toddlers. References were selected based on the criteria of 1) journals related to stunting prevention, health promotion, and maternal knowledge, 2) 2017-2021 published years, and 3) fully accessible journals.</p> <p><strong>Results:</strong> A total of 8362 journals were analyzed, but none of them fit the bill or had anything to do with how health education affects mothers' awareness of how to prevent stunting. The impact of health promotion on mothers' awareness of stunting prevention is then demonstrated from the 25 references found. In order to prevent stunting, health promotion involves a learning process that transforms bad behavior patterns into good ones.</p> <p><strong>Conclusion:</strong> Health promotion is a learning process carried out to change unhealthy behavior patterns into healthy behavior so that stunting can occur.</p> <p><strong>Keywords:</strong> Health promotion, knowledge, mothers, toddlers, stunting</p> <p>&nbsp;</p> <p><em><strong>Abstrak</strong></em></p> <p><em><strong>Latar Belakang:</strong> Promosi kesehatan masyarakat adalah untuk meningkatkan kapasitas masyarakat untuk bertindak melalui instruksi langsung dari dan untuk masyarakat umum, agar memungkinkan mereka bertanggung jawab atas kesejahteraan mereka sendiri. Selain itu juga bertujuan untuk mengembangkan program yang berbasis pada keterlibatan masyarakat dalam kegiatan sosial yang mendukung hidup sehat. Stunting mulai terjadi saat anak berusia dua tahun dan terjadi saat embrio masih berada di dalam kandungan. Stunting adalah kondisi ketika tingkat keburukan normal seseorang lebih tinggi dari tingkat keburukan normal orang lain. Tujuan mengetahui pengaruh promosi kesehatan terhadap pengetahuan ibu tentang pencegahan stunting pada balita.</em></p> <p><em><strong>Metode:</strong> Kajian pustaka dilakukan dengan mencari di situs ilmu langsung, Pubmed, dan google scholar. Menggunakan kata kunci Pengaruh promosi kesehatan terhadap pengetahuan ibu tentang pencegahan stunting pada balita. Referensi dipilih berdasarkan kriteria: 1) jurnal terkait pencegahan stunting, promosi kesehatan, dan pengetahuan ibu; 2) tahun terbit 2017-2021;&nbsp; 3) jurnal yang dapat diakses sepenuhnya.</em></p> <p><em><strong>Hasil:</strong> Sebanyak 8362 jurnal dianalisis, namun tidak ada satupun yang sesuai atau berkaitan dengan bagaimana pendidikan kesehatan mempengaruhi kesadaran ibu tentang cara mencegah stunting. Dampak promosi kesehatan terhadap kesadaran ibu tentang pencegahan stunting kemudian ditunjukkan dari 25 referensi yang ditemukan. </em></p> <p><em><strong>Kesimpulan:</strong> Untuk mencegah stunting, promosi kesehatan melibatkan proses pembelajaran yang mengubah pola perilaku buruk menjadi baik.</em></p> <p><em><strong>Kata kunci:</strong> Promosi kesehatan, pengetahuan, ibu, balita, stunting</em></p> 2022-12-31T13:48:27SE Asia Standard Time ##submission.copyrightStatement## http://ejournal2.litbang.kemkes.go.id/index.php/hsji/article/view/6473 Resilience and Emotional Intelligence Related to Workers' Stress Level in the Quarter Life Crisis 2022-12-31T14:42:56SE Asia Standard Time Ice Yulia Wardani iceyulia@ui.ac.id Diva Aisyah Oktaviana iceyulia@ui.ac.id Riska Amalya Nasution iceyulia@ui.ac.id <p><strong>Background: </strong>young adults are vulnerable to stress due to difficulty completing their developmental tasks, which would make them be trapped in a quarter-life crisis. Resilience and emotional intelligence are needed to minimize work stress. Objectives: to investigate the relationship between resilience and emotional intelligence with stress levels in workers during the quarter-life crisis.</p> <p><strong>Methods: </strong>A quantitative descriptive, correlative, and cross-sectional design was used for the research.</p> <p><strong>Results: </strong>57% of workers had low resilience, 51,9% had good emotional intelligence, and 68,6% experienced moderate stress. The results of the analysis identified a relationship between resilience and emotional intelligence with the stress level of workers during the quarter-life crisis in DKI Jakarta (p=0.001).</p> <p><strong>Conclusions: </strong>workers with high resilience and good emotional intelligence experience lower stress than workers with low resilience and low emotional intelligence. This study recommends regular screening of workers’ mental health by health services and also for educational institutes to include material on resilience, emotional intelligence, work stress, and quarter-life crisis. Researchers recommend cooperation between companies and mental health services.</p> <p>&nbsp;<strong>Keywords: </strong>emotional intelligence, quarter life crisis, resilience, work stress, workers</p> <p><strong><em>Abstrak</em></strong></p> <p><strong><em>Latar Belakang: </em></strong><em>dewasa muda rentan mengalami stres akibat sulit menyelesaikan tugas perkembangannya, sehingga dapat terjebak pada quarter life crisis. Resiliensi dan kecerdasan emosi dibutuhkan untuk meminimalkan stres kerja. Tujuan penelitian untuk mengetahui hubungan resiliensi dan kecerdasan emosi dengan tingkat stres pekerja pada masa quarter life crisis. </em></p> <p><strong><em>Metode:</em></strong><em> penelitian ini menggunakan desain kuantitatif deskriptif korelatif dan desain cross sectional. </em></p> <p><strong><em>Hasil:</em></strong><em> 57% pekerja memiliki resiliensi rendah, 51,9% pekerja mempunyai kecerdasan emosi baik, dan 68,6% pekerja mengalami stres sedang. </em><em>Hasil analisis mengidentifikasi adanya hubungan resiliensi dan kecerdasan emosi dengan tingkat stres pekerja pada masa quarter life crisis di DKI Jakarta (p=0,001). </em></p> <p><strong><em>Kesimpulan:</em></strong><em> pekerja dengan tingkat resiliensi tinggi dan kecerdasan emosi baik mengalami stres lebih rendah dibandingkan pekerja dengan resiliensi rendah dan kecerdasan emosi rendah. Penelitian ini merekomendasikan adanya skrining rutin kesehatan jiwa pekerja oleh pelayanan kesehatan serta institut pendidikan untuk memasukkan materi resiliensi, kecerdasan emosi, stres kerja, dan quarter life crisis. Peneliti merekomendasikan adanya kerja sama antara perusahaan dengan layanan kesehatan jiwa.</em></p> <p><strong><em>Kata kunci: </em></strong><em>kecerdasan emosional, pekerja, resiliensi, stres kerja, quarter life crisis</em></p> 2022-12-31T14:12:38SE Asia Standard Time ##submission.copyrightStatement## http://ejournal2.litbang.kemkes.go.id/index.php/hsji/article/view/6469 The Bacterial Susceptibility of Levofloxacin for Urinary Tract Infections Bacteria in Type 2 Diabetes Mellitus Patients 2022-12-31T14:42:58SE Asia Standard Time Zulfikar Dwi Kiswahyu Nindo mahyarudin@medical.untan.ac.id Mahyarudin Mahyarudin mahyarudin@medical.untan.ac.id Mardhia Mardhia mahyarudin@medical.untan.ac.id Andriani Andriani mahyarudin@medical.untan.ac.id <p><strong>Abstract</strong></p> <p><strong>Background:</strong> Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia, and can be associated with long term organ damage, organ dysfunction, and multiple organ failure. Type 2 DM causes high glucose levels in urine and suppression of the immune system, as in result it becomes a predisposing factor for urinary tract infections (UTIs). The antibiotic therapies that can be given in UTIs is levofloxacin which is effective against many types of bacteria that cause UTIs.This study aimed to determine the pattern of levofloxacin sensitivity against the bacteria that cause UTIs patients with type 2 DM.</p> <p><strong>Methods:</strong> The study used a descriptive method with a total sample of 22 bacterial isolates that had been isolated from UTIs patients with type 2 DM . The bacterial isolates were collections of the Microbiology Laboratory, Faculty of Medicine, Tanjungpura University. The study was conducted from June to October 2019. The antibiotic sensitivity test used the disc diffusion method and interpretation based on the Clinical &amp; Laboratory Standards Institute (CLSI).</p> <p><strong>Results:</strong> levofloxacin was sensitive to UTIs bacteria by 95,45% with a total of 21 isolates from 22 isolates. The levofloxacin sensitivity pattern which was sensitive to types of bacteria such as Escherichia coli (100%), Pseudomonas aeruginosa (100%), Enterobacter aerogenes (66,67%), Klebsiella sp. (100%), and Shigella sp. (100%).</p> <p><strong>Conclusion:</strong> levofloxacin is sensitive against bacteria that cause UTIs in type 2 DM patients with a percentage of 95,45%.</p> <p><strong>Keywords:</strong> Diabetes mellitus; Urinary Tract Infections; Levofloxacin<em>.</em></p> <p><strong><em>Abstrak</em></strong></p> <p><strong><em>Latar Belakang: </em></strong><em>Diabetes melitus (DM) merupakan penyakit gangguan metabolik menahun yang memiliki karakteristik berupa hiperglikemia, k</em><em>ondisi ini dapat berkaitan dengan kerusakan organ jangka panjang, disfungsi organ, dan kegagalan berbagai organ dalam tubuh. DM tipe 2 mengakibatkan tingginya kadar glukosa dalam urin dan penekanan sistem imun, sehingga dapat menjadi faktor predisposisi terhadap infeksi saluran kemih (ISK). Terapi antibiotik yang dapat diberikan pada ISK adalah levofloksasin yang efektif terhadap banyak jenis bakteri penyebab ISK. Penelitian ini bertujuan untuk mengetahui pola sensitivitas antibiotic levofloksasin terhadap bakteri penyebab infeksi saluran kemih pada pasien diabetes melitus tipe 2.</em></p> <p><strong><em>Metode</em></strong><em>: Penelitian menggunakan metode deskriptif dengan total sampel sebanyak 22 isolat bakteri yang telah diisolasi dari pasien ISK dengan DM tipe 2. Isolat bakteri merupakan koleksi Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Tanjungpura. Penelitian dilaksanakan pada bulan Juni – Oktober 2019. Pengujian sensitivitas antibiotik menggunakan metode difusi cakram dan menggunakan tabel Clinical &amp; Laboratory Standards Institute (CLSI) sebagai panduan kriteria.</em></p> <p><strong><em>Hasil: </em></strong><em>levofloksasin sensitif terhadap bakteri ISK sebesar 95,45% dengan jumlah isolat sebanyak 21 dari 22 isolat uji. Pola sensitivitas levofloksasin yang bersifat sensitif pada jenis bakteri yaitu Escherichia coli (100%), Pseudomonas aeruginosa (100%), Enterobacter aerogenes (66,67%), Klebsiella sp. (100%), dan Shigella sp. (100%).</em></p> <p><strong><em>Kesimpulan: </em></strong><em>levofloksasin sensitif terhadap bakteri penyebab ISK pada pasien DM tipe 2 dengan persentase sebesar 95,45%.</em></p> <p><strong><em>Kata kunci: </em></strong><em>Diabetes Melitus; Infeksi Saluran Kemih; Levofloksasin.</em></p> 2022-12-31T14:33:40SE Asia Standard Time ##submission.copyrightStatement## http://ejournal2.litbang.kemkes.go.id/index.php/hsji/article/view/6491 Construction of Recombinant Plasmids encoding the sACE2-Fc gene for the Development of SARS-CoV-2 Neutralization Test 2023-05-11T06:17:46SE Asia Daylight Time Fera Ibrahim fera0703@gmail.com Silvia Tri Widyaningtyas feraib@yahoo.fr Devia Puspita Natalicka feraib@yahoo.fr Ekawati Betty Pratiwi feraib@yahoo.fr <p><strong>Background:</strong> COVID-19 infection is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The presence of neutralizing antibodies in the body of an infected person is necessary to prevent viral infection. The presence of neutralizing antibodies in seroconvalesen or post vaccinated sera can be measured by several techniques. Competitive Elisa using recombinant RBD spike antigens and ACE2 receptors is one of techniques that viable to be developed since this technique can be applied in facility that does not have a BSL 2 facility. In &nbsp;this research was aimed at obtaining a recombinant plasmid that could be used for the production of the soluble ACE2 recombinant (sACE2). To enhanced its activity, the sACE2 was fused to the C-terminal portion of Imunoglobin F (Fc region).</p> <p><strong>Methods:</strong> The sACE2 coding gene was inserted within the NheI and BamHI sites replacing sRBD gene in the pcDNA3-SARS-CoV-2-S-RBD-Fc vector. The presence of sACE2 gene was confirmed using restriction enzyme analysis and sequencing.</p> <p><strong>Results:</strong> The result showed that the recombinant pcDNA3-sACE2(WT)-Fc plasmid was successfully verified using restriction enzymes and sequencing so that it can be used for the production of recombinant soluble ACE2 using mammalian cells.</p> <p><strong>Conclusions: </strong>The construction process of sACE2 into the pcDNA3 SARS-CoV-2-S-RBD-Fc was successfully carried out and verified.</p> <p><strong>Abstrak</strong></p> <p></p> <p><strong>Latar Belakang:</strong> Infeksi COVID-19 disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Keberadaan antibodi netralisasi dalam tubuh seseorang yang terinfeksi sangat diperlukan untuk mencegah infeksi virus. Antibodi netralisasi dalam serum konvalesen atau serum paska vaksinasi dapat di deteksi dengan beberapa teknik. Elisa kompetitif menggunakan antigen rekombinan RBD spike dan reseptor ACE2 merupakan salah satu teknik yang layak untuk dikembangkan karena teknik ini dapat diterapkan pada fasilitas yang tidak memiliki fasilitas BSL 2. Pada penelitian ini bertujuan untuk mendapatkan plasmid rekombinan yang dapat digunakan untuk produksi rekombinan <em>soluble</em> ACE2 (sACE2). Untuk meningkatkan aktivitasnya, sACE2 digabungkan ke bagian C- terminal dari Imunoglobulin F (Fc <em>region</em>).</p> <p><strong>Metode:</strong> Gen pengkode sACE2 dimasukkan ke dalam situs NheI dan BamHI menggantikan gen S-RBD dalam vektor pcDNA3-SARS-CoV-2-S-RBD-Fc. Keberadaan gen sACE2 dikonfirmasi menggunakan analisis restriksi enzim dan sekuensing.</p> <p><strong>Hasil:</strong> Hasil penelitian menunjukkan bahwa plasmid rekombinan pcDNA3-sACE2(WT)-Fc berhasil diverifikasi menggunakan enzim restriksi dan sekuensing sehingga dapat digunakan untuk produksi rekombinan <em>soluble </em>ACE2 menggunakan sel mamalia.</p> <p><strong>Kesimpulan: </strong>Proses konstruksi sACE2 kedalam plasmid pcDNA3-SARS-CoV-2-S-RBD-Fc telah berhasil dilakukan dan diverifikasi.&nbsp;</p> 2023-05-11T06:13:12SE Asia Daylight Time ##submission.copyrightStatement##