Pengaruh Atorvastatin 40 Mg Dalam Menurunkan Kadar Kolesterol Pada Penderita Hiperkolesterolemia

Abstract

Abstracts
The recommended dose of atorvastatin for respondents with hypercholesterolaemia is 10 mg to 80 mg. Many studies have proved that atorvastatin could decrease LDL level but not significantly lowered non-HDL cholesterol level. This research was conducted by using one pre-post experiment design with 92 samples of hypercholesterolemic respondents in Palembang city. Respondents were given 40 mg of atorvastatin for 10 days. The findings were atorvastatin dose 40 mg for 10 days effective in lowering cholesterol, triglyceride, HDL and LDL levels in patients with hypercholesterolemia significantly (p<0,05). The suggestion for further research is to investigate the effect of atorvastatin with hypercholesterolemia at doses lower than 40 mg.

Keywords: Cholesterol, Atorvastatin 40 mg, Hypercholesterolemia

Abstrak

Rentang dosis atorvastatin yang dianjurkan untuk respondenPenelitian ini dilakukan dengan menggunakan desain one pre-post experiment dengan 92 sampel responden hiperkolesterolemia di kota Palembang. Responden diberikan atorvastatin 40 mg selama 10 hari. Hasil temuan adalah atorvastatin dosis 40 mg selama 10 hari efektif dalam menurunkan kadar kolesterol, trigeliserid, HDL dan LDL pada responden hiperkolesterolemia secara signifikan (p<0,05). Saran untuk penelitian selanjutnya adalah melakukan penelitian pengaruh atorvastatin dengan hiperkolesterolemia pada dosis yang lebih rendah dari 40 mg.

Kata Kunci: Kolesterol, Atorvastatin 40 mg, Hiperkolesterolemia