Hubungan Kadar Glukosa Darah Terhadap Peningkatan Kadar Lemak Darah Pada Populasi Studi Kohor Kecamatan Bogor Tengah 2018

Abstract

Abstract

Dyslipidaemia is one of the risk factors for non communicable disease prevalence such as cardiovascular, diabetes mellitus, stroke, cancer, and obstructive chronic respiratory disease. Design of the study was cross sectional, which was part of the Cohort Biomedical Study for Risk Factor of Non Communicable Disease as well as Child Growth and Development in 2018. The subjects of the study were male and female aged 30 years above as many as 2092 respondents. The objective of the study was to figure out the association of blood glucose level with lipid profile as one of dyslipidaemia indicators. The study results showed 11.7% of the respondents had diabetes mellitus based on fasting glucose concentration ≥126 mg/dl and as many as 12.69% of the respondents had diabetes mellitus based on post-prandial glucose concentration ≥200 mg/dl. Meanwhile, more women tended to have low HDL level than men (34.0% vs 9.3%), 36.0% respondents had high cholesterol level (≥240 mg/dl), 20.1% of the respondents had very high LDL level (≥190 mg/dl) and 12.2% of the respondent had high triglyceride level (200-449 mg/dl). Data analysis showed there was a significant association between blood glucose level and lipid profile (p<0.05), especially for cholesterol and triglyceride levels. It can be concluded that blood glucose levels have a significant correlation with increasing blood fat levels.

Keywords: diabetes mellitus, dyslipidaemia, cohort biomedical study 2018

 Abstrak

Dislipidemia merupakan salah satu faktor risiko terhadap prevalensi penyakit tidak menular utama seperti kardiovaskular, diabetes melitus, strok, kanker, dan penyakit paru obstruktif kronik. Penelitian memiliki desain potong lintang, yang merupakan bagian dari penelitian Kohor Biomedis Faktor Risiko PTM dan TKA tahun 2018 dengan subjek responden laki-laki serta perempuan dewasa berusia lebih dari 30 tahun sebanyak 2092 responden. Tujuan penelitian adalah untuk mengetahui hubungan kadar glukosa darah terhadap profil lemak darah sebagai salah satu indikator dislipidemia. Hasil penelitian menunjukkan bahwa terdapat 11,7% responden menderita diabetes melitus dengan kadar glukosa puasa ≥126 mg/dl dan 12,69% responden mempunyai kadar glukosa darah 2 jam post prandial ≥200 mg/dl. Perempuan lebih cenderung memiliki kadar HDL rendah daripada laki-laki (34,0% vs 9,3%), Sebanyak 36,0% responden mempunyai kadar kolesterol tinggi (≥240 mg/dl), sebesar 20,1% responden memiliki kadar LDL yang sangat tinggi (≥190 mg/dl) dan 12,2% responden mempunyai kadar trigliserida tinggi (200-449 mg/dl). Analisis data menunjukkan terdapat hubungan yang signifikan antara kadar glukosa darah dengan kadar lemak darah (p<0,05), terutama kadar kolesterol dan trigliserida. Dapat disimpulkan bahwa kadar glukosa darah memiliki hubungan yang signifikan terhadap peningkatan kadar lemak darah.

 Kata kunci: diabetes melitus, dislipidemia, penelitian kohor biomedis 2018