SITUASI HUMAN IMMUNODEFICIENCY VIRUS-TUBERKULOSIS DI KABUPATEN MERAUKE 2018: ANCAMAN PADA UMUR PRODUKTIF

  • Dina Bisara Badan Penelitian dan Pengembangan Kesehatan Kemkes RI
  • Oster Suriani Simarmata Balitbangkes Kemkes RI
  • Novianti Novianti
  • Felly Philipus Senewe
Keywords: HIV, HIV Ko infeksi TBC, umur produktif, anak, RSUD Merauke

Abstract

Abstract

Background: Pulmonary tuberculosis is the most serious opportunistic infection in HIV/AIDS subjects and is a major cause of mortality and morbidity in developing countries.

Objective: To describe  the results of HIV / TB examination in Merauke District Hospital

Method: Study design is cross-sectional using data from “Studi evaluasi deteksi kasus TBC dengan alat tes cepat molekuler di Indonesia tahun 2018”. Descriptive data analysis is applied based on secondary data of PLWHA patients who visited Merauke District Hospital to examine Mycobacterium tuberculosis (MTB).

Results: The proportion of PLWHA was almost three times higher (8.5%) compared to other 43 health facilities (3,0%). The highest proportion of PLWHA is productive age of 15-54 years (94.9%) and male (54.5%). The proportion of children (aged <15 years) with HIV is six times higher (3%) compared to other 43 health facilities (0,5%). The results of MTB with molecular rapid tests in 43 health facilities is higher in PLWHA compared to non-PLWHA (34.4%:32.0%), and the opposite is true for Merauke District Hospital (22.2%:29.4%).

Conclussion: HIV epidemic in Merauke has been on the general population particularly in productive and children category. This high level of HIV has an impact on increasing transmission to children and HIV-TB co-infection.

Keywords: HIV, HIV-TB co-infection, reproductive age, children, RSUD Merauke

Abstrak

Latar belakang: Tuberkulosis paru adalah salah satu infeksi oportunistik yang paling serius pada HIV/AIDS dan merupakan penyebab utama kematian dan morbiditas di negara-negara berkembang.

Tujuan: Diperoleh gambaran hasil pemeriksaan HIV-TB di RSUD Merauke.

Metode: Disain studi adalah potong lintang menggunakan data “Studi evaluasi deteksi kasus TB dengan alat tes cepat molekuler (TCM) di Indonesia tahun 2018”. Analisis deskriptif data sekunder pasien HIV yang berkunjung ke RSUD Merauke yang diperiksa MTB.

Hasil: Proporsi ODHA di RSUD Merauke hampir tiga kali lebih tinggi (8,5%) dibandingkan dengan 43 fasilitas kesehatan lainnya (3,0%). Persentase tertinggi adalah pada umur produktif 15-54 tahun (94,9%) dan laki-laki (54,5%). Proporsi anak (<15 tahun) dengan HIV enam kali lebih tinggi (3,0%) dibandingkan dengan 43 fasilitas kesehatan lainnya (0,5%). Hasil pemeriksaan konfirmasi bakteriologi MTB dengan TCM pada 43 fasilitas kesehatan tinggi pada ODHA dibanding non ODHA (34,4%:32,0%), dan situasi sebaliknya pada RSUD Merauke (22,2%:29,4%).

Kesimpulan: Epidemi HIV di Merauke sudah mencapai tingkat populasi umum, terutama pada kelompok produktif dan anak. Tingginya angka HIV akan berdampak pada tingginya penularan pada anak dan koinfeksi HIV-TB.

 

Kata kunci: HIV, HIV koinfeksi TB, umur produktif, anak, RSUD Merauke

References

1. UNAIDS UNAIDS Data 2017. (2017).
2. Kementerian Kesehatan, R. I. Estimasi dan Proyeksi HIV / AIDS di Indonesia Tahun 2011-2016. (2016).
3. WHO GLOBAL TUBERCULOSIS REPORT. (2012).
4. Corbett, E. L. et al. The Growing Burden of Tuberculosis. ARCH Intern Med 163, 1009–1021 (2003).
5. Kementerian Kesehatan, R. I. HIV epidemiology review Indonesia 2016. 1–66 (2016).
6. Dinas Kesehatan Merauke Profil Kesehatan Kabupaten Merauke 2017. (2017).
7. Kementerian Kesehatan Profil Kesehatan Indonesia 2017. (2018).
8. WHO Global Tuberculosis Report 2018. (2018).
9. National Center for HIV/AIDS VH, STD, and T. P. D. of H. P. HIV and Tuberculosis. (2018).
10. WHO WHO policy on collaborative TB / HIV activities Guidelines for national programmes and other stakeholders. (2012).
11. Martinson, N. A., Hoffmann, C. J. & Chaisson, R. E. Epidemiology of Tuberculosis and HIV Recent Advances in Understanding and Responses. Proc Am Thorac Soc 8, 288–293 (2011).
12. Kementerian Kesehatan Indonesia Survei Terpadu Biologis dan Perilaku Pada Masyarakat Umum di Tanah Papua 2013. (2014).
13. UNAIDS GLOBAL AIDS UPDATE. (2016).
14. Weller S and Davis K Condom effectiveness in reducing heterosexual HIV transmission. PubMed (2002).
15. Dina Bisara Lolong & Lamria Pangaribuan Perilaku Pengguna Kondom Dalam Pencegahan Penularan HIV pada MAsyarakat Umum ditanah Papua dan PAda Kelompok Risiko di Indonesia, 2004-2006. Indonesia Journal of Health Ecology 10, 1144–1154. (2010).
16. UNAIDS Report CHildREn And PREGnAnT wOmEn liVinG wiTH HiV. (2014).
17. Kementerian Kesehatan Statistik Kasus HIV/AIDS di Indonesia sampai Desember 2013. (2013).
18. UNAIDS GLOBAL REPORT on the global AIDS epidemic 2013. (2013).
19. WHO HIV-Associated Tuberculosis. (2018).
20. UNAIDS Global report: UNAIDS report on the global AIDS epidemic 2013. (2013).
21. WHO A guide to monitoring and evaluation for collaborative TB/HIV activities. (2015).
22. Pathmanathan, I. et al. Incidence and predictors of tuberculosis among HIV-infected adults after initiation of antiretroviral therapy in Nigeria , 2004-2012. PLOS 2004–2012 (2017).doi:10.1371/journal.pone.0173309
23. Ali, A. et al. Prevalence of Pulmonary Tuberculosis in HIV / AIDS Subjects. Austin Virol and Retrovirology 3, 3–5 (2016).
24. Tesfaye, B. et al. The twin epidemics : Prevalence of TB / HIV co- infection and its associated factors in Ethiopia ; A systematic review and meta-analysis. 1–18 (2018).doi:10.1371/journal.pone.0203986
25. Mirna Widiyanti, Eva Fitriana, E. I. Karakteristik pasien koinfeksi tb-hiv di rumah sakit mitra masyarakat mimika papua. 49–55 (2015).
26. Elfride Irawati & Rusnaeni PROFIL PASIEN KO-INFEKSI TUBERCULOSE-HIV DI RSUD DOK II JAYAPURA Tuberculosis-HIV Co-infection Profile in DOK II Hospital Jayapura PROFIL PASIEN KO-INFEKSI TUBERCULOSE-HIV DI RSUD DOK II JAYAPURA Tuberculosis-HIV Co-infection Profile in DOK II Hospital Ja. IJAS 7, (2017).
27. Pontororing, G. J. et al. The burden and treatment of HIV in tuberculosis patients in Papua Province , Indonesia : a prospective observational study. BMC Infectious Diseases 10, 362 (2010).
28. Teweldemedhin, M., Asres, N., Gebreyesus, H. & Asgedom, S. W. Tuberculosis-Human Immunodeficiency Virus ( HIV ) co-infection in Ethiopia : a systematic review and meta-analysis. BMC infectious diseases 9, 1–9 (2018).
29. Tshitenge, S. et al. A mortality review of tuberculosis and HIV co-infected patients in Mahalapye , Botswana : Does cotrimoxazole preventive therapy and / or antiretroviral therapy protect against death ? African Journal of Primary Health Care & Family Medicine 1–5 (2015).
30. Marcy, O. et al. Articles Mortality and its determinants in antiretroviral treatment-naive HIV-infected children with suspected tuberculosis : an observational cohort study. THE LANCET 3018, 1–9 (2017).
31. Newell, M. et al. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa : a pooled analysis. THE LANCET 364, 1236–1243 (2004).
Published
2019-12-31
How to Cite
1.
Bisara D, Simarmata O, Novianti N, Senewe F. SITUASI HUMAN IMMUNODEFICIENCY VIRUS-TUBERKULOSIS DI KABUPATEN MERAUKE 2018: ANCAMAN PADA UMUR PRODUKTIF. kespro [Internet]. 31Dec.2019 [cited 6May2024];10(1):1-. Available from: http://ejournal2.litbang.kemkes.go.id/index.php/kespro/article/view/1711