Pengaruh Meniran (Phyllanthus niruri L) Terhadap Patogenesis lnfeksi Salmonella

  • Sunarno Sunarno Puslitbang Biomedis dan Farmasi Badan Litbang Kesehatan, Depkes RI
Keywords: Phyllantus niruri L, Immunomodulator, Salmonella


Typhoid/paratyphoid disease is a major problem in Indonesia. Management of therapy including the use of immunomodulator must be developed continuously. In this case Phyllanthus niruri L is immunomodulator that has been usefitl to increase the animal and human immunity. The purpose of this stun) was to know the influence of Phyllanthus niruri L on the Salmonella infection focusing on spleen bacterial colonies. The experiment was designed with post test-only control group to 18 Bab/C Mice infected by Salmonella typhimurium divided into one control group and two experimental groups which hmie given Phyllanthus niruri L of 3x 0.125 mg/day (P1) and 3x 0.25 mg/day (P2) orally. Statistical analysis was used Oneway ANOVA test. The research result showed that treatmen P1 had significant influence to decrease spleen bacterial colonies compared to control group.


How to Cite
Sunarno S. Pengaruh Meniran (Phyllanthus niruri L) Terhadap Patogenesis lnfeksi Salmonella. jki [Internet]. 25Jun.2009 [cited 2Oct.2022];1(2):71-6. Available from: