Efek Mutagenik Ekstrak Etanol Daun Kembang Sungsang (Gloriosa superba L.)

  • Dian Sundari Pusat Penelitian dan Pengembangan Gizi dan Makanan
  • Pudjiastuti Pudjiastuti Pusat Penelitian Biomedis dan Farmasi
Keywords: Kembang sungsang (Gloriosa superba Linn.), Leaf extract, mutagenic activity

Abstract

Eflicacy of a plant can be caused by chemical compounds contain, on the other hand can cause toxic eflects. Toxic ejfects of chemicals can be defined as the potential of chemicals to poison the bodies of people who are exposed kembang sungsang (Gloriosa superba Linn.) including Colchicaceae families. Plants used empirically for treatment of Gout, diuretic, rheumatism, etc. Mutagenicity is a test to determine the possibility of compounds are mutagens. To see if these plants have the effect of mutagens, mutagenicity tests performed 70% ethanol extract of the leaves Kembang sungsang. Mutagenicity studies conducted by the Ames method using five test bacterial strains that have been transferred are.‘ Salmonella typhimurium TA 98, TA 100, TA 1535, TA 1537 and Escherichia colt WP2uvrA with and without metabolic activator S-9. The dose tested was 125, Z50, 500, 1000, and 2000 ul /plate. As a negative control was DMSO solution of 100 ul /plate. The results showed that the mutagenic test 70% ethanol extract of leaves Kembang sztngsang. with the addition aktivator without the addition of S-9 did not have the eflect of mutagens.

References

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Published
2009-10-26
How to Cite
1.
Sundari D, Pudjiastuti P. Efek Mutagenik Ekstrak Etanol Daun Kembang Sungsang (Gloriosa superba L.). jki [Internet]. 26Oct.2009 [cited 21May2022];1(3):77-2. Available from: https://ejournal2.litbang.kemkes.go.id/index.php/jki/article/view/2848
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Articles