Profil Penggunaan Obat Antiinflamasi Nonstreoid di Indonesia

  • Maratu Soleha
  • Ani Isnawati 1 Puslitbang Biomedis dan Teknologi Dasar Kesehatan, Badan Penelitian dan Pengembangan Kesehatan
  • Nyoman Fitri 1 Puslitbang Biomedis dan Teknologi Dasar Kesehatan, Badan Penelitian dan Pengembangan Kesehatan
  • Rosa Adelina 1 Puslitbang Biomedis dan Teknologi Dasar Kesehatan, Badan Penelitian dan Pengembangan Kesehatan,
  • Hamim Tsalis Soblia Badan Pusat Statistik
  • Winarsih Winarsih 1 Puslitbang Biomedis dan Teknologi Dasar Kesehatan, Badan Penelitian dan Pengembangan Kesehatan
Keywords: Rheumatism, Inflamation, Nonsteroid antiinflamation drugs

Abstract

Nonsteroid Antiinflamation Drugs (NSAIDs) are available in drug store and be bought as a pain relief. Basic Health Research (Riskesdas) 2013 study the medicines stored in household. Basic Health Research (Riskesdas) 2013 was held in 33 provinces and 497 districts in Indonesia. The research encompasses 300.000 households in 12.000 blocks cencus. The participants were designated households and its member of the family. The study were interviewing the participants to obtain data of all drugs that are stored and used, including traditional medicines. The data including the brand, indication, the provenance (prescribed or unprescribed by doctor), the storage period and also observe drug condition. This study was further analysis of subset data in block IV of Riskesdas 2013 in households. The data were classified by its mechanism and its structure. The result showed that East Java was the highest user of AINS drugs was (15%). Non selectif COX-2 drug and partial selectif COX-2 was 38,3% bought from drug store and 14,4% from drug store. For rheumatism treatment was all used for more than a month. Widely use of NSAIDs as a pain relief indicated the necessity of a proper medicine use information to avoid side effect of NSAID drug.

References

1. Kementerian Kesehatan Republik Indonesia. Laporan hasil Riset Kesehatan Dasar Indonesia (Riskesdas) tahun 2013. Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. 2013. Jakarta.
2. Tjay TH, Rahardja K. Obat obat penting edisi ke 7. Gramedia Jakarta. ISBN 978602 02 64806. 2015.
3. Dixit M, Doan T, Kirschner R, Dixit N. Significant acute kidney Injury due to non-steroidal antiinflammatory drugs: inpatient setting. Pharmaceuticals. 2010; 3: 1279-85; doi.10.3390/ph 3041279. ISSN. 1424-8247.
4. Manurung KUS. Pola penggunaan obat dalam upaya pasien melakukan pengobatan sendiri di beberapa apotek. Skripsi. Universitas Sumatera Utara. 2010.
5. Epstein RM, Street RL. Share mind: communication decision making and autonomy in serious illness. Annals of Family Medicine. 2011;9(5):454-61. doi 10.1370/afm.1301
6. Ananda DAE, Liza P, Hidayah R. Hubungan tingkat pengetahuan dan perilaku swamedikasi natrium diklofenak di apotek. Jurnal Pharmacy. 2013;10(2):138-46
7. Supardi S, Susyanty AL. Penggunaan obat tradisional dalam upaya pengobatan sendiri di Indonesia (Analisis data Susenas tahun 2007). Buletin Penelitian Kesehatan. 2010;38(2):80-9.
8. Siahaan SA, Usia T, Pujiati S, Tarigan IU, Murhandini S, Isfandari S, et al. Pengetahuan, sikap, dan perilaku masyarakat dalam memilih obat yang aman di tiga Provinsi di Indonesia. Jurnal Kefarmasian Indonesia. 2017;7(2):136-45
9. Waranugraha Y, Suryana BPP, Pratomo B. Hubungan pola penggunaan OAINS dengan gejala klinis gastropati pada pasien rematik. Jurnal Ilmu Kedokteran. 2010;26(2):107-112
10. Zarghi A, Arfaei S. Selective COX-2 inhibitor: a review of their structure activity relationship. Iran Journal of Pharmaceutical Research. 2011;10(4):55-83.
11. Hasanah m, Carolina N, Berawi KN, Soleha T. Drug prescribing pattern in the early management of rheumatoid artritis patient in a hospital in Bandar Lampung period July 2012 until June 2013. Medical Journal of Lampung University. 2014; 3(5):113-22
12. Almi DY. Hemetemesis melena at causa gastritis erosif dengan riwayat penggunaan obat NSAID pada pasien laki-laki lanjut usia. Medula. 2013; 1(1):72-9.
13. Saepudin, Wiranti W. Kualitas peresepan obat golongan antiinflamasi nonsteroid di salah satu Rumah Sakit Swasta di Yogyakarta. Jurnal Farmasi Indonesia. 2008;4(1):47-54
14. Lelo A, Rangkuti Z, Pane YS. Penggunaan anti-inflamasi non-steroid yang rasional pada penanggulangan nyeri rematik. Tugas akhir. 2004. Fakultas Kedokteran Universitas Sumatra Utara.
15. Rekomendasi Perhimpunan Rheumatologi Indonesia (IRA) tentang Penggunaan obat antiinflamasi non steroid. ISBN 978-979-3730-22-6. Diunduh Tanggal 20/07/2016. http://reumatologi.or.id/var/rekomendasi/Rekomendasi_IRA_OAINS_2014.pdf
16. Wang Z, Chen JQ, Liu JL. COX-2 Inhibitor and gastric cancer. Gastroenterology Research and Practice. 2014:1-7 http//dx.doi: 10.1155/2014/132320
17. Jerosch J. Effects of glucosamine and chondroitin sulfate on cartilage metabolism in OA: outlook on other nutrient partners especially omega-3 fatty acids. International Journal of Rheumatology. 2011:1-17
18. Herowati R. Obat dan suplemen untuk osteoarthritis. Pharmacy. 2013;11(1):40-8.
Published
2018-10-16
How to Cite
1.
Soleha M, Isnawati A, Fitri N, Adelina R, Soblia H, Winarsih W. Profil Penggunaan Obat Antiinflamasi Nonstreoid di Indonesia. jki [Internet]. 16Oct.2018 [cited 14Nov.2018];8(2):109-17. Available from: https://ejournal2.litbang.kemkes.go.id/index.php/jki/article/view/316
Section
Articles