HUBUNGAN TINGKAT STRES DENGAN KEJADIAN HIPERTIROID PADA WANITA USIA SUBUR
Abstract
Latar Belakang. Hipertiroid dapat mengakibatkan percepatan detak jantung, penurunan berat badan, peningkatan nafsu makan, dan kecemasan. Hipertiroidisme lebih sering terjadi pada wanita. Pajanan asap rokok, stres psikologi, penggunaan kontrasepsi hormonal, umur, periode melahirkan, dan konsumsi iodium pada tahap tertentu dapat memicu hipertiroid. Tujuan. Penelitian ini mencari hubungan antara status merokok, tingkat stres, penggunaan kontrasepsi hormonal, umur, dan penggunaan garam beriodium rumah tangga dengan kejadian hipertiroid pada wanita usia subur (WUS). Metode. Penelitian ini adalah penelitian observasional dengan desain kasus-kontrol pada pasien baru WUS berusia 15–49 tahun di Klinik GAKI Magelang tahun 2013–2014. Populasi penelitian terdiri atas kelompok kasus yaitu 51 pasien WUS didiagnosis hipertiroid. Kelompok kontrol yaitu 102 WUS yang didiagnosis sehat dan tidak mengalami gangguan fungsi tiroid (eutiroid/normal). Data dikumpulkan melalui wawancara responden disertai uji cepat kandungan iodium garam rumah tangga. Uji Chi-square dilakukan untuk mendapatkan hubungan bivariat antara variabel independen dan kejadian hipertiroid pada responden. Analisis uji regresi logistik dilakukan untuk mendapatkan hubungan variabel dependen secara bersamaan terhadap kejadian hipertiroid. Hasil. Wanita usia subur dengan stres berat mempunyai risiko hipertiroid 2,4 kali daripada WUS dengan stres ringan (OR=2,435; 95% CI=1,031–5,755; p=0,043; p<0,05). Wanita usia subur bukan pengguna kontrasepsi hormonal memiliki risiko hipertiroid 3,5 kali dibandingkan dengan WUS pengguna kontrasepsi hormonal (OR=0,284; 95% CI=0,114–0,709; p=0,007; p<0,05). Kesimpulan. Stres berat berhubungan dengan risiko hipertiroid pada WUS. Wanita usia subur (WUS) hendaknya melakukan manajemen stres sebagai salah satu upaya pencegahan terhadap hipertiroid dan juga pencegahan kekambuhan hipertiroid.
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